Design, Synthesis, and Biological Evaluation of Pyrazolo[1,5-a]pyridine-3-carboxamides as Novel Antitubercular Agents
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چکیده
منابع مشابه
Synthesis and biological evaluation of some novel 1,4-dihydropyridines as potential antitubercular agents.
Recent studies showed that 1,4-dihydropyridine-3,5-dicarbamoyl derivatives with lipophilic groups have significant antitubercular activity. In this study, we have synthesized new derivatives of 1,4-dihydropyridines bearing carbmethoxy and carbethoxy group at C-3 and C-5 of the 1,4-dihydropyridine ring. In addition, 1H-pyrazole ring is substituted at C-4 position. These analogues were synthesize...
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ژورنال
عنوان ژورنال: ACS Medicinal Chemistry Letters
سال: 2015
ISSN: 1948-5875,1948-5875
DOI: 10.1021/acsmedchemlett.5b00176